Hamlet Versus Othello: Or, Why the White Boy Keeps Winning

Why leptin keeps you warma

If a good layer of insulating fat would be sufficient to stay warm, leptin deficient ob/ob mice should do fine in a cold environment since they are massively obese. But once exposed to low temperatures, ob/ob mice rapidly die of hypothermia. Even at ambient temperatures ob/ob mice have a core body temperature that is 2 C lower than that of wild type littermates [1]. This hypothermia can be norm...

Animals Versus Animats: Or Why Not Model the Real Iguana?

The overlapping fields of 'Adaptive Behaviour' and 'Artificial Life' are often described as novel approaches to biology. They focus attention on bottom-up explanations, and how lifelike phenomena can result from relatively simple systems interacting dynamically with their environments. They are also characterised by the use of synthetic methodologies, that is, building artificial systems as a m...

The Psychology of Hamlet

Shakespeare’s Hamlet ominously begins with Horatio and Marcellus discussing the appearance of a ghostly apparition that strangely resembles the King of Denmark. As the play unfolds, we learn that it is, in fact, the ghost of Hamlet Sr., the King of Denmark. Immediately, the play begins with a sense of foreboding danger for all of those involved who have a direct connection with his son Hamlet, ...

Nephrologists Versus Peripherally Inserted Central Catheters: Are the PICCs Winning?

Because of their low rate of procedure-related complications, ease of placement, and favorable cost profile, peripherally inserted central venous catheters (PICCs) have increased in prevalence (1–3). In patients with difficult to obtain intravenous access, PICCs are a reasonable form of central venous access when repeated administration of intravenous therapy and/or phlebotomy is required. Alth...

Solving Single-suit Bridge Play: Winning and Knowing Why